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Article

Gene expression profiling of human aortic endothelial cells exposed to disturbed flow and steady laminar flow

10 Apr 2002

Abstract excerpt

Subtraction cloning and cDNA arrays were used to compare steady-state mRNA levels in cultured human aortic endothelial cells (HAEC) exposed for up to 24 h to either high-shear (13 dyn/cm(2)) steady laminar flow (LF), an established representation of "atheroprotective" flow conditions, or low-shear (<1 dyn/cm(2)), pulsatile, nonsteady, non-unidirectional flow (disturbed flow, DF) that simulates conditions in the...

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PMID: 11948288
DOI: 10.1152/physiolgenomics.00075.2001

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