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HDAC11, an emerging therapeutic target for metabolic disorders

20 Oct 2022

Abstract excerpt

Histone deacetylase 11 (HDAC11) is the only member of the class IV HDAC, and the latest member identified. It is highly expressed in brain, heart, kidney and some other organs, and located in mitochondria, cytoplasm and nuclei, depending on the tissue and cell types. Although studies in HDAC11 total knockout mice suggest its dispensable features for tissue development and life, it participates in diverse...

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PMID: 36339432
DOI: 10.3389/fendo.2022.989305

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