Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhanced gene expression conferred by stepwise modification of a nonprimate lentiviral vector.

Human gene therapy - 1 Dec 2007

Sinn Patrick L, Goreham-Voss Jessica D, Arias Ariadna C, Hickey Melissa A, Maury Wendy, Chikkanna-Gowda C P, McCray Paul B

Abstract excerpt

The practical application of gene transfer as a treatment for genetic diseases such as cystic fibrosis or hemophilia has been hindered, in part, by low efficiencies of vector delivery and transgene expression. We demonstrated that a feline immunodeficiency virus (FIV)-based lentiviral vector pseudotyped with the envelope glycoprotein from the baculovirus Autographa californica (GP64) efficiently transduces and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Baculoviridae
Share to Codon, Initiator

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Factor VIII

Share to Gene Products, gag

Share to Hepatocytes

Share to Immunodeficiency Virus, Feline

Share to Lentivirus

Share to Transduction, Genetic

Source

Identifiers

PMID: 18052720
DOI: 10.1089/hum.2006.127

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhanced gene expression conferred by stepwise modification of a nonprimate lentiviral vector.PMID 18052720Read ↗

Assessment of F/HN-Pseudotyped Lentivirus as a Clinically Relevant Vector for Lung Gene TherapySemantic proximity Read ↗

Cocal-pseudotyped Lentiviral Vectors Resist Inactivation by Human Serum and Efficiently Transduce Primate Hematopoietic Repopulating CellsSemantic proximity Read ↗

Lentiviral Vector Pseudotypes: Precious Tools to Improve Gene Modification of Hematopoietic Cells for Research and Gene TherapySemantic proximity Read ↗

Factors Influencing the Titer and Infectivity of Lentiviral VectorsSemantic proximity Read ↗

Lentivirus Vector Can Be Readministered to Nasal Epithelia without Blocking Immune ResponsesSemantic proximity Read ↗

GP64-pseudotyped lentiviral vectors target liver endothelial cells and correct hemophilia A miceSemantic proximity Read ↗

Correction of bleeding diathesis without liver toxicity using arenaviral-pseudotyped HIV-1-based vectors in hemophilia A mice.Semantic proximity Read ↗

Cystic fibrosis gene therapy: a mutation-independent treatment.Semantic proximity Read ↗

Lentiviral Vector Gene Transfer to Porcine AirwaysSemantic proximity Read ↗

Long-term correction of hemophilia A mice following lentiviral mediated delivery of an optimized canine factor VIII gene.Semantic proximity Read ↗

Phenotypic correction of a mouse model of hemophilia A using AAV2 vectors encoding the heavy and light chains of FVIII.Semantic proximity Read ↗

Genetic alteration of SJ293TS cells and modification of serum-free media enhances lentiviral vector productionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.