Article
Polymorphism in the Calpain 10 gene influences glucose metabolism in human fat cells.
Diabetologia - 1 Feb 2002
Hoffstedt J, Rydén M, Löfgren P, Orho-Melander M, Groop L, Arner P
Abstract excerpt
AIMS/HYPOTHESIS: A common G to A polymorphism ( UCSNP-43) in the Calpain 10 gene was recently found to be associated with Type II (non-insulin-dependent) diabetes mellitus and variations in post-absorptive and insulin stimulated glucose metabolism in vivo. We aimed to study the influence of Calpain 10 polymorphism on insulin action in fat cells. METHODS: Calpain 10 polymorphism ( UCSNP-19, -43 or -63) were set in...
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