Article
Structural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10.
The Journal of biological chemistry - 14 Jun 2002
Lin Yaqiong, Hwang William C, Basavappa Ravi
Abstract excerpt
Cell cycle progression is controlled at several different junctures by the targeted destruction of cell cycle regulatory proteins. These carefully orchestrated events include the destruction of the securin protein to permit entry into anaphase, and the destruction of cyclin B to permit exit from mitosis. These destruction events are mediated by the ubiquitin/proteasome system. The human ubiquitin-conjugating...
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