Article
Selection of metastatic tumour phenotypes by host immune systems.
Lancet (London, England) - 4 Dec 1999
Seymour K, Pettit S, O'Flaherty E, Charnley R M, Kirby J A
Abstract excerpt
Metastasis and the processes underlying this phenomenon make epithelial cancers so malignant. Local control of cancers by surgery is sometimes possible but locoregional and distant recurrence commonly lead to the failure of treatment with ensuing morbidity and mortality. Tumour cells express a range of new antigens during growth and there are opportunities for the host immune system to interact with these...
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