Article
Intragenic deletion in the Desmoglein 4 gene underlies the skin phenotype in the Iffa Credo "hairless" rat.
Differentiation; research in biological diversity - 1 Oct 2004
Bazzi Hisham, Kljuic Ana, Christiano Angela M, Christiano Angela M, Panteleyev Andrey A
Abstract excerpt
The Iffa Credo (IC) "hairless" rat is an autosomal recessive hypotrichotic animal model actively used in pharmacological and dermatological studies. Although the molecular basis of the IC rat phenotype was never defined, the designation "hr/hr" (hairless) has been used for this rat mutation. Despite the observation that IC rats share many phenotypic similarities with Charles River (CR) 'hairless rats',...
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