Article
Antioxidant enzymes and paraoxonase show a co-activity in preserving low-density lipoprotein from oxidation.
Clinical and experimental medicine - 1 Dec 2001
Sözmen E Y, Sözmen B, Girgin F K, Delen Y, Azarsiz E, Erdener D, Ersöz B
Abstract excerpt
Oxidative modification of low-density lipoprotein in the artery wall plays a crucial role in the development of atherosclerosis. This physiopathological mechanism is clearly inhibited by high-density lipoprotein possibly via paraoxonase enzyme activity, present in high-density lipoprotein. In this study, we determined the in vitro susceptibility of low-density lipoprotein to oxidation and the effect of various...
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