Article
Relevance of variants in serum antiproteinases for the course of chronic pancreatitis.
Scandinavian journal of gastroenterology - 1 Mar 2002
Teich N, Walther K, Bödeker H, Mössner J, Keim V
Abstract excerpt
BACKGROUND: Mutations of the pancreatic serine protease inhibitor, Kazal type 1 (SPINK1), the cationic trypsinogen (PRSS1) and the cystic fibrosis transmembrane conductance regulator (CFTR) were reported to be genetic risk factors of chronic pancreatitis (CP). The aim of this study was to determine the role of genetic variants of the main serum antiproteinases alpha-1-antitrypsin (AAT) and alpha-2-macroglobulin...
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