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Article

Purification and unique properties of mammary epithelial stem cells.

Nature - 23 Feb 2006

Stingl John, Eirew Peter, Ricketson Ian, Shackleton Mark, Vaillant François, Choi David, Li Haiyan I, Eaves Connie J

Abstract excerpt

Elucidation of the cellular and molecular mechanisms that maintain mammary epithelial tissue integrity is of broad interest and paramount to the design of more effective treatments for breast cancer. Evidence from both in vitro and in vivo experiments suggests that mammary cell differentiation is a hierarchical process originating in an uncommitted stem cell with self-renewal potential. However, analysis of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16395311
DOI: 10.1038/nature04496

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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