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Article

Neuroprotection and dopamine agonists

1 Feb 2002

Abstract excerpt

Several factors are known to be capable of inducing relatively selective dopaminergic cell death in the substantia nigra and inducing the clinical features that characterize Parkinson's disease (PD). Neuronal toxins such as 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) can induce parkinsonism in human and animal models, and rotenone, another specific mitochondrial complex I inhibitor, can induce similar...

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PMID: 11909981
DOI: 10.1212/wnl.58.suppl_1.s9

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