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Neurotoxic Mechanism and Shortcomings of MPTP, 6-OHDA, Rotenone and Paraquat-induced Parkinson’s Disease Animal Models

2020-11-05

Abstract excerpt

: Parkinson’s disease (PD) has caused most economies to lose their active human capital. Due to poor understanding of the pathophysiology of PD, PD animal models were developed to aid the investigation of PD pathogenesis and therapy. Currently, the toxin-induced and the genetic animal models are being used for most PD research. Most neurotoxin animal model studies on PD are focused on the motor features and econom...

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Literature Corpus work
92896c50-87b8-52b6-9344-670a4b3cccc0
DOI
10.2174/2666121701999201104163407
Open publication

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Neurotoxic Mechanism and Shortcomings of MPTP, 6-OHDA, Rotenone and Paraquat-induced Parkinson’s Disease Animal ModelsDOI 10.2174/2666121701999201104163407
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