Article
Prospects for new restorative and neuroprotective treatments in Parkinson's disease.
Nature - 24 Jun 1999
Dunnett S B, Björklund A
Abstract excerpt
The degeneration of forebrain dopamine systems in Parkinson's disease has been an effective target for pharmaceutical research over the past four decades. However, although dopamine replacement may alleviate the symptoms of the disease, it does not halt the underlying neuronal degeneration. The past decade has seen major advances in identifying discrete genetic and molecular causes of parkinsonism and mapping the...
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