Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The viral transactivator E1A regulates the mouse mammary tumor virus promoter in an isoform- and chromatin-specific manner.

The Journal of biological chemistry - 31 May 2002

Soeth Edlyn, Thurber Denise B, Smith Catharine L

Abstract excerpt

Proteins encoded by the adenovirus E1A gene regulate both cellular and viral genes to mediate effects on cell cycle, differentiation, and cell growth control. We have identified the mouse mammary tumor virus (MMTV) promoter as a target of E1A action and investigated the role nucleoprotein structure plays in its response to E1A. Both 12 and 13 S forms target the MMTV promoter when it has a disorganized and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenovirus E1A Proteins
Share to Chromatin
Share to Fluorescent Antibody Technique, Indirect

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Vectors

Share to Luciferases

Share to Mammary Tumor Virus, Mouse

Share to Microscopy, Fluorescence

Share to Protein Isoforms

Source

Identifiers

PMID: 11909860
DOI: 10.1074/jbc.M200629200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The viral transactivator E1A regulates the mouse mammary tumor virus promoter in an isoform- and chromatin-specific manner.PMID 11909860Read ↗

Epigenetic reprogramming by adenovirus e1a.Semantic proximity Read ↗

The Epstein–Barr virus nuclear antigen-1 reprograms transcription by mimicry of high mobility group A proteinsSemantic proximity Read ↗

The Adenoviral Oncogene E1A-13S Interacts with a Specific Isoform of the Tumor Suppressor PML To Enhance Viral TranscriptionSemantic proximity Read ↗

PLDLS-dependent interaction of E1A with CtBP: regulation of CtBP nuclear localization and transcriptional functions.Semantic proximity Read ↗

ALY is a common coactivator of RUNX1 and c-Myb on the type B leukemogenic virus enhancer.Semantic proximity Read ↗

Transcriptional control by adenovirus E1A conserved region 3 via p300/CBP.Semantic proximity Read ↗

Sp1 and ETS family transcription factors regulate the mouse Mta2 gene expression.Semantic proximity Read ↗

Tumor-specific activation of hTERT-derived promoters by tumor suppressive E1A-mutants involves recruitment of p300/CBP/HAT and suppression of HDAC-1 and defines a combined tumor targeting and suppression system.Semantic proximity Read ↗

Adenovirus E1A Targets the DREF Nuclear Factor To Regulate Virus Gene Expression, DNA Replication, and GrowthSemantic proximity Read ↗

A variant binding sequence for transcription factor EBP-80 confers increased promoter activity on a retroviral long terminal repeat.Semantic proximity Read ↗

Adenovirus small e1a alters global patterns of histone modification.Semantic proximity Read ↗

Cell cycle-mediated regulation of smooth muscle alpha-actin gene transcription in fibroblasts and vascular smooth muscle cells involves multiple adenovirus E1A-interacting cofactors.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.