Article
Association of the collagen type 1 (COL1A 1) Sp1 binding site polymorphism to femoral neck bone mineral density and wrist fracture in 1044 elderly Swedish women.
Calcified tissue international - 1 Mar 2004
Gerdhem P, Brändström H, Stiger F, Obrant K, Melhus H, Ljunggren O, Kindmark A, Akesson K
Abstract excerpt
Identification of risk factors for osteoporosis has been essential for understanding the development of osteoporosis and related fragility fractures. A polymorphism of the binding site for the transcription factor Sp1 of the collagen I alpha 1 gene (COLIA1) has shown an association to bone mass and fracture, but the findings have not been consistent, which may be related to population differences. The Sp1...
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