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Article

Identification of a novel splice-site mutation in the CYP1A2 gene.

British journal of clinical pharmacology - 1 Sept 2003

Allorge Delphine, Chevalier Dany, Lo-Guidice Jean-Marc, Cauffiez Christelle, Suard Françoise, Baumann Pierre, Eap Chin B, Broly Franck

Abstract excerpt

AIMS: To identify the molecular basis for a low CYP1A2 metabolic status, as determined by a caffeine phenotyping test, in a 71-year-old, nonsmoking, Caucasian woman who presented with very high clozapine concentrations despite being administered a standard dose of the drug. METHODS: The nucleotid...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12919186
DOI: 10.1046/j.1365-2125.2003.01858.x
PMCID: PMC1884342

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12919186-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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