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Article

Human herpesvirus-6 rep/U94 gene product has single-stranded DNA-binding activity

1 Apr 2002

Abstract excerpt

The characterization is reported of the human herpesvirus-6B (HHV-6B) rep/U94 gene, which is a homologue of the adeno-associated virus type 2 rep. In this study, a monoclonal antibody was produced against HHV-6B REP (anti-REP mAb). Immunofluorescence staining using the anti-REP mAb showed that REP was localized to the nucleus in HHV-6-infected MT4 cells. It was first detected at 24 h post-infection (p.i.) and...

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PMID: 11907335
DOI: 10.1099/0022-1317-83-4-847

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