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Expression of Human Herpesvirus 6B <i>rep</i> within Infected Cells and Binding of Its Gene Product to the TATA-Binding Protein In Vitro and In Vivo

1 Jul 2000

Abstract excerpt

We have characterized the human herpesvirus 6B (HHV-6B) rep gene, which is a homologue of the adeno-associated virus type 2 rep and is unique in the herpesvirus family. Three transcripts, 9.0, 5.0, and 2. 7 kb (the major transcript), were detected by Northern blotting using an HHV-6B rep probe under late conditions. We investigated the expression kinetics of the rep gene using cycloheximide (CHX) and...

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PMID: 10846093
DOI: 10.1128/jvi.74.13.6096-6104.2000

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