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Article

Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis.

Proceedings of the National Academy of Sciences of the United States of America - 19 Mar 2002

Okamoto Shu-ichi, Li Zhen, Ju Chung, Scholzke Marion N, Mathews Emily, Cui Jiankun, Salvesen Guy S, Bossy-Wetzel Ella, Lipton Stuart A

Abstract excerpt

Myocyte enhancer factor-2 (MEF2) transcription factors are activated by p38 mitogen-activated protein kinase during neuronal and myogenic differentiation. Recent work has shown that stimulation of this pathway is antiapoptotic during development but proapoptotic in mature neurons exposed to excit...

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Identifiers

PMID: 11904443
DOI: 10.1073/pnas.022036399
PMCID: PMC122633

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-11904443-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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