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Caspase-Independent Programmed Cell Death Following Ischemic Stroke

1 Jan 2008

Abstract excerpt

There is accumulating evidence that caspase-independent programs play a significant role in delayed neuronal death following ischemic stroke. Previous research has implicated mitochondrial proteins, such as apoptosis-inducing factor (AIF) and Bcl-2/adenovirus E1B 19 kDa-interacting protein (BNIP3), as players involved in this pathway. More recent work has begun to hone in on the specific interactions between...

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PMID: 18569435
DOI: 10.1080/08941930802029945

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