Article
How does tmRNA move through the ribosome?
FEBS letters - 6 Mar 2002
Ivanov Pavel V, Zvereva Maria I, Shpanchenko Olga V, Dontsova Olga A, Bogdanov Alexey A, Aglyamova Galina V, Lim Valery I, Teraoka Yoshika, Nierhaus Knud H
Abstract excerpt
To test the structure of tmRNA in solution, cross-linking experiments were performed which showed two sets of cross-links in two different domains of tmRNA. Site-directed mutagenesis was used to search for tmRNA nucleotide bases that might form a functional analogue of a codon-anticodon duplex to be recognized by the ribosomal A-site. We demonstrate that nucleotide residues U85 and A86 from tmRNA are significant...
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