Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mechanisms of resistance to imipenem in imipenem-resistant, ampicillin-sensitive Enterococcus faecium.

APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Nov 2001

El Amin N, Lund B, Tjernlund A, Lundberg C, Jalakas K, Wretlind B

Abstract excerpt

Enterococcus faecium has six penicillin-binding proteins (PBP), where PBP5 seems to be the main target for beta-lactam antibiotics. The PBP profiles of three imipenem-resistant, ampicillin-sensitive E. faecium strains, isolated from the same patient, were studied using biotinylated ampicillin and chemiluminescence detection. Imipenem resistance in these strains was found to be associated with hyperproduction of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ampicillin
Share to Ampicillin Resistance

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Enterococcus faecium

Share to Hexosyltransferases

Share to Imipenem

Share to Muramoylpentapeptide Carboxypeptidase

Share to Penicillin-Binding Proteins

Share to Peptidyl Transferases

Source

Identifiers

PMID: 11900060
DOI: 10.1034/j.1600-0463.2001.d01-148.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mechanisms of resistance to imipenem in imipenem-resistant, ampicillin-sensitive Enterococcus faecium.PMID 11900060Read ↗

Modification of penicillin-binding protein 5 associated with high-level ampicillin resistance in Enterococcus faeciumSemantic proximity Read ↗

Differential Penicillin-Binding Protein 5 (PBP5) Levels in the Enterococcus faecium Clades with Different Levels of Ampicillin Resistance.Semantic proximity Read ↗

Role of Penicillin-Binding Protein 5 in Expression of Ampicillin Resistance and Peptidoglycan Structure in Enterococcus faeciumSemantic proximity Read ↗

Penicillin-binding protein 5 sequence alterations in clinical isolates of Enterococcus faecium with different levels of beta-lactam resistance.Semantic proximity Read ↗

Structure of the low-affinity penicillin-binding protein 5 PBP5fm in wild-type and highly penicillin-resistant strains of Enterococcus faeciumSemantic proximity Read ↗

Polymorphisms of the pbp5 gene and correlation with ampicillin resistance in Enterococcus faecium isolates of animal origin.Semantic proximity Read ↗

Evaluation of polymorphisms in pbp4 gene and genetic diversity in penicillin-resistant, ampicillin-susceptible Enterococcus faecalis from hospitals in different states in Brazil.Semantic proximity Read ↗

Polymorphism in pbp5 gene detected in clinical Enterococcus faecium strains with different ampicillin MICs from a Tunisian hospital.Semantic proximity Read ↗

Genome-wide identification of ampicillin resistance determinants in Enterococcus faecium.Semantic proximity Read ↗

Analysis of PBP5 of Early U.S. Isolates of Enterococcus faecium: Sequence Variation Alone Does Not Explain Increasing Ampicillin Resistance over TimeSemantic proximity Read ↗

Single point mutations in global regulatory genes restore cephalosporin resistance in a low-MIC <i>Enterococcus faecium</i> natural isolateSemantic proximity Read ↗

Single point mutations in global regulatory genes restore cephalosporin resistance in a low-MIC Enterococcus faecium natural isolate.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.