Article
Genome-wide identification of ampicillin resistance determinants in Enterococcus faecium.
PLoS genetics - 1 Jun 2012
Zhang Xinglin, Paganelli Fernanda L, Bierschenk Damien, Kuipers Annemarie, Bonten Marc J M, Willems Rob J L, van Schaik Willem
Abstract excerpt
Enterococcus faecium has become a nosocomial pathogen of major importance, causing infections that are difficult to treat owing to its multi-drug resistance. In particular, resistance to the β-lactam antibiotic ampicillin has become ubiquitous among clinical isolates. Mutations in the low-affinity penicillin binding protein PBP5 have previously been shown to be important for ampicillin resistance in E. faecium,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.