Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Developmental changes in adipose and muscle lipoprotein lipase activity in the atherosclerosis-prone JCR:LA-corpulent rat.

International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity - 1 Mar 2002

Mantha L, Russell J C, Brindley D N, Deshaies Y

Abstract excerpt

OBJECTIVE: To characterize the developmental changes in adipose and muscle lipoprotein lipase (LPL) activity in the atherosclerosis-prone JCR:LA-corpulent rat, and to test the hypothesis that tissue-specific abnormalities in LPL activity precede the establishment of obesity. DESIGN: Lean (+/?) and obese cp/cp male JCR:LA rats were studied at 4, 5 and 8 weeks of age, that is at the onset of obesity, and at a time...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipose Tissue
Share to Arteriosclerosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Body Composition

Share to Fatty Acids, Nonesterified

Share to Leptin

Share to Lipoprotein Lipase

Share to Organ Size

Share to Rats, Mutant Strains

Source

Identifiers

PMID: 11896485
DOI: 10.1038/sj.ijo.0801882

Genes

LPL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Developmental changes in adipose and muscle lipoprotein lipase activity in the atherosclerosis-prone JCR:LA-corpulent rat.PMID 11896485Read ↗

Adipose-specific lipoprotein lipase deficiency more profoundly affects brown than white fat biology.Semantic proximity Read ↗

Lipoprotein lipase expression exclusively in liver. A mouse model for metabolism in the neonatal period and during cachexia.Semantic proximity Read ↗

Induced mutant mice expressing lipoprotein lipase exclusively in muscle have subnormal triglycerides yet reduced high density lipoprotein cholesterol levels in plasma.Semantic proximity Read ↗

The prolactin-deficient mouse has an unaltered metabolic phenotype.Semantic proximity Read ↗

Increasing adipocyte lipoprotein lipase improves glucose metabolism in high fat diet-induced obesity.Semantic proximity Read ↗

Effects of heterozygous lipoprotein lipase deficiency on diet-induced atherosclerosis in mice.Semantic proximity Read ↗

Combined lipase deficiency in the mouse. Evidence of impaired lipase processing and secretion.Semantic proximity Read ↗

Exaggerated stress-induced release of nonesterified fatty acids in JCR:LA-corpulent rats.Semantic proximity Read ↗

Inactive lipoprotein lipase (LPL) alone increases selective cholesterol ester uptake in vivo, whereas in the presence of active LPL it also increases triglyceride hydrolysis and whole particle lipoprotein uptake.Semantic proximity Read ↗

Relationship between lipoprotein lipase and high density lipoprotein cholesterol in mice: modulation by cholesteryl ester transfer protein and dietary status.Semantic proximity Read ↗

Increased thermoregulation in cold-exposed transgenic mice overexpressing lipoprotein lipase in skeletal muscle: an avian phenotype?Semantic proximity Read ↗

Pancreatic triglyceride lipase deficiency minimally affects dietary fat absorption but dramatically decreases dietary cholesterol absorption in mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.