Article
Increased sensitivity to nicotine-induced seizures in mice heterozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor.
Neuroreport - 11 Feb 2002
Gil Ziv, Sack Ram A, Kedmi Merav, Harmelin Alon, Orr-Urtreger Avi
Abstract excerpt
alpha7 Nicotinic acetylcholine receptors (nAChRs) are sparsely distributed throughout the peripheral and central nervous systems. Several studies have suggested that central alpha7 nicotinic receptors may influence sensitivity to nicotine-induced seizures in mice. In order to investigate the effe...
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