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Article

Bone tumorigenesis induced by alpha-particle radiation: mapping of genetic loci influencing predisposition in mice.

Radiation research - 1 Apr 2002

Rosemann Michael, Lintrop Mare, Favor Jack, Atkinson Michael J

Abstract excerpt

The present study was carried out to determine the extent to which genetic factors modify the incidence of radiation-induced bone tumorigenesis in mice, and to map putative susceptibility genes. We conducted a genome-wide linkage analysis in a cohort of 47 interstrain backcrossed mice. After the mice were injected with the bone-seeking alpha-particle-emitting radionuclide (227)Th, 21 of the mice developed...

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Identifiers

PMID: 11893245
DOI: 10.1667/0033-7587(2002)157[0426:btibap]2.0.co;2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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