Article
The genetics of radiation-induced and sporadic osteosarcoma: a unifying theory?
Journal of radiological protection : official journal of the Society for Radiological Protection - 1 Sept 2002
Rosemann Michael, Kuosaite Virginija, Nathrath Michaela, Atkinson Michael J
Abstract excerpt
Cancer is a disease of the genome, with the neoplastic phenotype being passed from one cell generation to the other. Radiation-induced cancer has often been considered to represent a unique entity amongst neoplasia, with the energy deposition being held responsible for both direct (gene mutations) and indirect (bystander effects, induced instability etc) alterations to the cellular genome. However, radiogenic...
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