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Article

Alternate Translation Occurs within the Core Coding Region of the Hepatitis C Viral Genome

1 May 2002

Abstract excerpt

The majority of hepatitis C virus (HCV) isolates contain an open reading frame (ORF) overlapping with the core coding sequences in the +1 frame, which was assumed to be untranslated. We present evidence supporting the expression of this ORF (designated core+1 ORF) via novel translation mechanisms. First, fusion of the luciferase gene with the HCV-1 core+1 ORF followed by in vitro translation resulted in the...

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Identifiers

PMID: 11884417
DOI: 10.1074/jbc.m201722200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Alternate Translation Occurs within the Core Coding Region of the Hepatitis C Viral GenomePMID 11884417Read ↗

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