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Article

Two alternative translation mechanisms are responsible for the expression of the HCV ARFP/F/core+1 coding open reading frame.

The Journal of biological chemistry - 17 Oct 2003

Vassilaki Niki, Mavromara Penelope

Abstract excerpt

HCV-1 produces a novel protein, known as ARFP, F, or core+1. This protein is encoded by an open reading frame (ORF) that overlaps the core gene in the +1 frame (core+1 ORF). In vitro this protein is produced by a ribosomal frameshift mechanism. However, similar studies failed to detect the ARFP/F/core+1 protein in the HCV-1a (H) isolate. To clarify this issue and to elucidate the functions of this protein, we...

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Identifiers

PMID: 12874283
DOI: 10.1074/jbc.M305504200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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