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Article

DNA damage and mutations induced by arachidonic acid peroxidation.

Biochemistry - 30 Dec 2003

Lim Punnajit, Sadre-Bazzaz Kianoush, Shurter Jesse, Sarasin Alain, Termini John

Abstract excerpt

Endogenous cellular oxidation of omega6-polyunsaturated fatty acids (PUFAs) has long been recognized as a contributing factor in the development of various cancers. The accrual of DNA damage as a result of reaction with free radical and electrophilic aldehyde products of lipid peroxidation is believed to be involved; however, the genotoxic and mutation-inducing potential of specific membrane PUFAs remains poorly...

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Identifiers

PMID: 14690412
DOI: 10.1021/bi035555w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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