Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Correlation between tRNALys3 aminoacylation and its incorporation into HIV-1.

The Journal of biological chemistry - 17 May 2002

Javanbakht Hassan, Cen Shan, Musier-Forsyth Karin, Kleiman Lawrence

Abstract excerpt

During human immunodeficiency virus type 1 (HIV-1) assembly, tRNA(Lys) is selectively packaged into the virus, where tRNA(Lys3) serves as the primer for reverse transcription. Lysyl-tRNA synthetase is also selectively incorporated into HIV-1 and is therefore a strong candidate for being the signal by which viral proteins interact with tRNA(Lys) isoacceptors. Previously, mutations in the tRNA(Lys3) anticodon have...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anticodon
Share to COS Cells
Share to Electrophoresis, Gel, Two-Dimensional

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nucleic Acid Conformation

Share to RNA, Transfer, Lys

Share to Virion

Share to Virus Assembly

Source

Identifiers

PMID: 11884398
DOI: 10.1074/jbc.M112479200

Genes

CGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Correlation between tRNALys3 aminoacylation and its incorporation into HIV-1.PMID 11884398Read ↗

The Role of Pr55 gag in the Annealing of tRNA 3 Lys to Human Immunodeficiency Virus Type 1 Genomic RNASemantic proximity Read ↗

Role of Pr160gag-pol in mediating the selective incorporation of tRNA(Lys) into human immunodeficiency virus type 1 particlesSemantic proximity Read ↗

Profiling non-lysyl tRNAs in HIV-1Semantic proximity Read ↗

Ability of wild-type and mutant lysyl-tRNA synthetase to facilitate tRNA(Lys) incorporation into human immunodeficiency virus type 1.Semantic proximity Read ↗

Effects of modifying the tRNA(3Lys) anticodon on the initiation of human immunodeficiency virus type 1 reverse transcription.Semantic proximity Read ↗

Molecular mimicry of human tRNALys anti-codon domain by HIV-1 RNA genome facilitates tRNA primer annealing.Semantic proximity Read ↗

Forced selection of tRNA(Glu) reveals the importance of two adenosine-rich RNA loops within the U5-PBS for SIV(smmPBj) replication.Semantic proximity Read ↗

New insights into inhibition of human immunodeficiency virus type 1 replication through mutant tRNALys3.Semantic proximity Read ↗

Switching the in vitro tRNA usage of HIV-1 by simultaneous adaptation of the PBS and PAS.Semantic proximity Read ↗

The Interaction of APOBEC3G with Human Immunodeficiency Virus Type 1 Nucleocapsid Inhibits tRNA <sub>3</sub> <sup>Lys</sup> Annealing to Viral RNASemantic proximity Read ↗

Importance of A-loop complementarity with tRNAHis anticodon for continued selection of tRNAHis as the HIV reverse transcription primer.Semantic proximity Read ↗

The tRNA primer activation signal in the human immunodeficiency virus type 1 genome is important for initiation and processive elongation of reverse transcription.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.