Article
Switching metal ion coordination and DNA Recognition in a Tandem CCHHC-type zinc finger peptide.
Inorganic chemistry - 15 Apr 2013
Besold Angelique N, Oluyadi Abdulafeez A, Michel Sarah L J
Abstract excerpt
Neural Zinc Finger Factor-1 (NZF-1) and Myelin Transcription Factor 1 (MyT1) are two homologous nonclassical zinc finger (ZF) proteins that are involved in the development of the central nervous system (CNS). Both NZF-1 and MyT1 contain multiple ZF domains, each of which contains an absolutely conserved Cys2His2Cys motif. All three cysteines and the second histidine have been shown to coordinate Zn(II); however,...
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