Article
Molecular assessment of lymph nodes in patients with resected stage I non-small cell lung cancer: preliminary results of a prospective study.
The Journal of thoracic and cardiovascular surgery - 1 Mar 2002
Ahrendt Steven A, Yang Stephen C, Wu Li, Roig Carmen M, Russell Pamela, Westra William H, Jen Jin, Brock Malcolm V, Heitmiller Richard F, Sidransky David
Abstract excerpt
OBJECTIVES: Routine histologic examination of resected lymph nodes in patients with stage I non-small cell lung cancer may underestimate the incidence of advanced disease. The presence of occult lymph node metastases may predict a higher risk of recurrence after intended curative resection. The purpose of this study was to determine the prognostic significance of TP53 and K-ras mutations in histologically...
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