Article
Expression profiling of non-small cell lung carcinoma identifies metastatic genotypes based on lymph node tumor burden.
The Journal of thoracic and cardiovascular surgery - 1 May 2004
Hoang Chuong D, D'Cunha Jonathan, Tawfic Sherif H, Gruessner Angelika C, Kratzke Robert A, Maddaus Michael A
Abstract excerpt
OBJECTIVE: This study hypothesized that non-small cell lung carcinoma cells from primary tumors isolated by laser capture microdissection would exhibit gene expression profiles associated with graded lymph node metastatic cell burden. METHODS: Non-small cell lung carcinoma tumors (n = 15) were classified on the basis of nodal metastatic cell burden by 2 methods, obtaining 3 groups: no metastasis, micrometastasis,...
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