Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Calcineurin-dependent regulation of Crz1p nuclear export requires Msn5p and a conserved calcineurin docking site.

Genes & development - 1 Mar 2002

Boustany Leila M, Cyert Martha S

Abstract excerpt

Calcineurin, a conserved Ca(2+)/calmodulin-regulated protein phosphatase, plays a crucial role in Ca(2+) signaling in a wide variety of cell types. In Saccharomyces cerevisiae, calcineurin positively regulates transcription in response to stress by dephosphorylating the transcription factor Crz1p/Tcn1p. Dephosphorylation promotes Crz1p nuclear localization in part by increasing the efficiency of its nuclear...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Active Transport, Cell Nucleus
Share to Amino Acid Motifs
Share to Calcineurin

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Nucleus

Share to Conserved Sequence

Share to Karyopherins

Share to Protein Sorting Signals

Share to Trans-Activators

Source

Open in PubMed Open full text

Identifiers

PMID: 11877380
DOI: 10.1101/gad.967602
PMCID: PMC155349

Genes

NES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Calcineurin-dependent regulation of Crz1p nuclear export requires Msn5p and a conserved calcineurin docking site.PMID 11877380Read ↗

A conserved family of calcineurin regulators.Semantic proximity Read ↗

Calcineurin acts through the CRZ1/TCN1-encoded transcription factor to regulate gene expression in yeast.Semantic proximity Read ↗

Elucidation of the calcineurin-Crz1 stress response transcriptional network in the human fungal pathogen Cryptococcus neoformans.Semantic proximity Read ↗

The eukaryotic response regulator Skn7p regulates calcineurin signaling through stabilization of Crz1p.Semantic proximity Read ↗

CRZ1, a target of the calcineurin pathway in Candida albicans.Semantic proximity Read ↗

Calcineurin Targets Involved in Stress Survival and Fungal VirulenceSemantic proximity Read ↗

NF-AT activation requires suppression of Crm1-dependent export by calcineurin.Semantic proximity Read ↗

Calcineurin Regulatory Subunit Calcium-Binding Domains Differentially Contribute to Calcineurin Signaling in Saccharomyces cerevisiae.Semantic proximity Read ↗

Partial Inhibition of Calcineurin Activity by Rcn2 as a Potential Remedy for Vps13 Deficiency.Semantic proximity Read ↗

Calcineurin‐dependent dephosphorylation of the transcription factor CrzA at specific sites controls conidiation, stress tolerance, and virulence of Aspergillus fumigatusSemantic proximity Read ↗

Conserved and Diverged Functions of the Calcineurin-Activated Prz1 Transcription Factor in Fission Yeast.Semantic proximity Read ↗

The Crz1/Sp1 Transcription Factor of Cryptococcus neoformans Is Activated by Calcineurin and Regulates Cell Wall IntegritySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.