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Article

The eukaryotic response regulator Skn7p regulates calcineurin signaling through stabilization of Crz1p.

The EMBO journal - 2 Jul 2001

Williams K E, Cyert M S

Abstract excerpt

To survive ionic, pH and pheromone stress, the yeast Saccharomyces cerevisiae activates signaling through the Ca2+-activated phosphatase calcineurin to the transcription factor Crz1p/Tcn1p. We show that the overexpression of SKN7, a response-regulator transcription factor, activates transcription from a calcineurin/Crz1p-dependent response element (CDRE). Ca2+-induced, calcineurin/Crz1p-dependent activation of...

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Identifiers

PMID: 11432834
DOI: 10.1093/emboj/20.13.3473
PMCID: PMC125528

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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