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Article

G/A1947 polymorphism in catechol-O-methyltransferase (COMT) gene in Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 May 1997

Xie T, Ho S L, Li L S, Ma O C

Abstract excerpt

High and low catechol-O-methyltransferase (COMT) activity is significantly determined by thermostability, which is caused by a valine/methionine108 polymorphism associated with polymorphic G/A1947 bases, in exon 4 of the COMT gene. Our allelic association study on this polymorphism did not find any statistically significant difference between our Chinese Parkinson's disease and that of control subjects. These...

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Source

Identifiers

PMID: 9159741
DOI: 10.1002/mds.870120325

Genes

COMT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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