Article
The multivalent PDZ domain-containing protein CIPP is a partner of acid-sensing ion channel 3 in sensory neurons.
The Journal of biological chemistry - 10 May 2002
Anzai Naohiko, Deval Emmanuel, Schaefer Lionel, Friend Valerie, Lazdunski Michel, Lingueglia Eric
Abstract excerpt
Acid-sensing ion channels (ASICs) are cationic channels activated by extracellular pH. They are present in the brain, where they are thought to participate in signal transduction associated with local pH variations, and in sensory neurons, where they have been involved in pain perception associated with tissue acidosis and in mechanoperception. The ASIC3 subunit is mainly expressed in dorsal root ganglion...
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