Article
Varied assembly and RNA editing efficiencies between genotypes I and II hepatitis D virus and their implications.
Hepatology (Baltimore, Md.) - 1 Mar 2002
Hsu Sheng-Chieh, Syu Wan-Jr, Sheen I-Jane, Liu Hui-Ting, Jeng King-Song, Wu Jaw-Ching
Abstract excerpt
The mechanisms that link genotypes of hepatitis D virus (HDV) with clinical outcomes have not yet been elucidated. Genotypic variations are unevenly distributed along the sequences of hepatitis delta antigens (HDAgs). Of these variations, the packaging signal at the C-terminus has a divergence of 74% between genotypes I and II. In this report, we address the issue of whether these high variations between...
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