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Article

Interaction and replication activation of genotype I and II hepatitis delta antigens.

Journal of virology - 1 Mar 2004

Hsu Sheng-Chieh, Wu Jaw-Ching, Sheen I-Jane, Syu Wan-Jr

Abstract excerpt

The nucleotide sequences of hepatitis D viruses (HDV) vary 5 to 14% among isolates of the same genotype and 23 to 34% among different genotypes. The only viral-genome-encoded antigen, hepatitis delta antigen (HDAg), has two forms that differ in size. The small HDAg (HDAg-S) trans-activates viral replication, while the large form (HDAg-L) is essential for viral assembly. Previously, it has been shown that the...

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Identifiers

PMID: 14990689
DOI: 10.1128/jvi.78.6.2693-2700.2004
PMCID: PMC353722

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Source receipt: pubmed, retrieved 7 Sept 2026.

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