Article
The rate of aneuploidy is altered in spermatids from infertile mice.
Human reproduction (Oxford, England) - 1 Mar 2002
Oppedisano L, Haines G, Hrabchak C, Fimia G, Elliott R, Sassone-Corsi P, Varmuza S
Abstract excerpt
BACKGROUND: It is now possible for infertile males to father their own genetic children through the technique of ICSI. This prospect has consequently prompted several investigations into the quality of sperm being retrieved from infertile males. One potential risk is the use of aneuploid sperm or spermatids, which might then be transferred to the fertilized oocyte. METHODS: In this investigation, aneuploidy of...
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