Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Natural selection on the erythrocyte surface.

Molecular biology and evolution - 1 Mar 2002

Baum Jake, Ward Ryk H, Conway David J

Abstract excerpt

Surface glycoproteins are principal receptors used by pathogens to invade target cells. It has been suggested that mammalian erythrocyte surface glycoproteins function as decoy receptors attracting pathogens to the anucleated erythrocyte and away from their target tissues. Glycophorin A (GYPA) is solely expressed on the erythrocyte surface where it is the most abundant sialoglycoprotein, although its function is...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Conserved Sequence
Share to Erythrocytes
Share to Glycophorins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Membrane Glycoproteins

Share to Primates

Share to Protein Structure, Tertiary

Share to Selection, Genetic

Share to Sequence Homology

Source

Identifiers

PMID: 11861881
DOI: 10.1093/oxfordjournals.molbev.a004075

Genes

GYPA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Natural selection on the erythrocyte surface.PMID 11861881Read ↗

Effects of natural selection and gene conversion on the evolution of human glycophorins coding for MNS blood polymorphisms in malaria-endemic African populations.Semantic proximity Read ↗

Genetic variation of glycophorins and infectious disease.Semantic proximity Read ↗

Resistance to malaria through structural variation of red blood cell invasion receptorsSemantic proximity Read ↗

The interplay between Siglecs and sialylated pathogensSemantic proximity Read ↗

A novel locus of resistance to severe malaria in a region of ancient balancing selection.Semantic proximity Read ↗

Genetic Evidence for Erythrocyte Receptor Glycophorin B Expression Levels Defining a Dominant Plasmodium falciparum Invasion Pathway into Human ErythrocytesSemantic proximity Read ↗

Sialic Acids as Receptors for PathogensSemantic proximity Read ↗

A natural history of FUT2 polymorphism in humans.Semantic proximity Read ↗

Large-scale sequencing of the CD33-related Siglec gene cluster in five mammalian species reveals rapid evolution by multiple mechanismsSemantic proximity Read ↗

Glycophorin B is the erythrocyte receptor of <i>Plasmodium falciparum</i> erythrocyte-binding ligand, EBL-1Semantic proximity Read ↗

Rapidly evolving genes in human. I. The glycophorins and their possible role in evading malaria parasites.Semantic proximity Read ↗

Multiple Genomic Events Altering Hominin SIGLEC Biology and Innate Immunity Predated the Common Ancestor of Humans and Archaic Hominins.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.