Article
Chromatin structure and gene regulation in the immune system.
Annual review of immunology - 1 Jan 2002
Smale Stephen T, Fisher Amanda G
Abstract excerpt
The development of the immune system and the host response to microbial infection rely on the activation and silencing of numerous, differentially expressed genes. Since the mid-1980s, a primary goal has been to identify transcription factors that regulate specific genes and specific immunological processes. More recently, there has been a growing appreciation of the role of chromatin structure in gene...
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