Article
Monitoring of donor/recipient T-cell engraftment kinetics in myeloablative allogeneic stem cell transplantation using short tandem repeat amplification from cell lysates.
Leukemia & lymphoma - 1 Jun 2002
Boumah C E, Meyer B, Aljurf M, Bertilsson P A B, Pyle R H, Al-Hussein K A F, Iqbal A, Gyger M
Abstract excerpt
Molecular monitoring of donor/recipient T-cell kinetics early post-transplant can provide clues to the immunological events that govern host-versus-graft reaction (HVGR) and graft versus-host-disease (GVHD). We have previously used fluorescence in situ hybridization (FISH) with X and Y probes to monitor recipient T (R-T) cell clearance early after myeloablative allogeneic stem cell transplantation (ASCT). We...
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