Article
The effect of relevant genotypes on PAH exposure-related biomarkers.
Journal of exposure analysis and environmental epidemiology - 1 Jan 2002
Kuljukka-Rabb Terhi, Nylund Lars, Vaaranrinta Raija, Savela Kirsti, Mutanen Pertti, Veidebaum Toomas, Sorsa Marja, Rannug Agneta, Peltonen Kimmo
Abstract excerpt
Polycyclic aromatic hydrocarbons (PAHs) in coke oven emissions cause a cancer risk to humans. In a comprehensive biomonitoring study among Estonian coke oven workers, we looked at the effect of genetic polymorphisms in metabolic enzymes on urinary mutagenicity, 1-hydroxypyrene (1-OHP) concentration in urine, and aromatic DNA adducts in white blood cells (WBCs). Coke oven workers were sampled twice (samplings I...
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