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Article

The influence of metabolic gene polymorphisms on urinary 1-hydroxypyrene concentrations in Chinese coke oven workers.

The Science of the total environment - 1 Aug 2007

Chen Bo, Hu Yunping, Jin Taiyi, Lu Daru, Shao Minhua, Zheng Lixing, Wang Qiangyi, Shen Yue, Liu Hongliang, Liu Yanhong, Zhou Yuanfen

Abstract excerpt

Urinary 1-hydroxypyrene (1-OHP), a biomarker of polycyclic aromatic hydrocarbons (PAHs) exposure, may be influenced by metabolic gene polymorphisms. Such knowledge could benefit us in understanding the inter-individual difference in the mechanism of PAHs-induced carcinogenesis. We investigated the influence of gene polymorphisms on urinary 1-OHP concentrations in 447 coke oven workers from two coking plants in...

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Source

Identifiers

PMID: 17498780
DOI: 10.1016/j.scitotenv.2007.02.021

Genes

GSTP1
GSTT1
EPHX1
EPHX2

Variants

rs2066853

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The influence of metabolic gene polymorphisms on urinary 1-hydroxypyrene concentrations in Chinese coke oven workers.PMID 17498780Read ↗

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[Effect of genetic polymorphisms of microsomal epoxide hydrolase on urinary 1-hydroxypyrene levels in coke oven workers].Semantic proximity Read ↗

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Glutathione S-transferase M1 and P1 genotypes and urinary excretion of 1-hydroxypyrene in coke oven workers.Semantic proximity Read ↗

GSTM1 and GSTT1 Genes are Associated With DNA Damage of p53 Gene in Coke-oven Workers.Semantic proximity Read ↗

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Associations between 25 lung cancer risk-related SNPs and polycyclic aromatic hydrocarbon-induced genetic damage in coke oven workers.Semantic proximity Read ↗

Genetic variations of CYP2B6 gene were associated with plasma BPDE-Alb adducts and DNA damage levels in coke oven workers.Semantic proximity Read ↗

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Association of polymorphisms in AhR, CYP1A1, GSTM1, and GSTT1 genes with levels of DNA damage in peripheral blood lymphocytes among coke-oven workers.Semantic proximity Read ↗

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