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Article

Role of p73 in malignancy: tumor suppressor or oncogene?

Cell death and differentiation - 1 Mar 2002

Stiewe T, Pützer B M

Abstract excerpt

The recently identified p53 family member, p73, shows substantial structural and functional homology with p53. However, despite the established role of p53 as a proto-type tumor suppressor, a similar function of p73 in malignancy is questionable. Overexpression of p73 can activate typical p53-responsive genes, and activation of p73 has been implicated in apoptotic cell death induced by aberrant cell proliferation...

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Identifiers

PMID: 11859406
DOI: 10.1038/sj.cdd.4400995

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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