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Article

DNp73 a matter of cancer: mechanisms and clinical implications.

Biochimica et biophysica acta - 1 Apr 2008

Buhlmann Sven, Pützer Brigitte M

Abstract excerpt

The p53 family proteins carry on a wide spectrum of biological functions from differentiation, cell cycle arrest, apoptosis, and chemosensitivity of tumors. NH2-terminally truncated p73 (referred to as DNp73) acts as a potent inhibitor of all these tumor suppressor properties, implying that it has oncogenic functions in human tumorigenesis. This was favored by the observation that high DNp73 expression levels in...

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Identifiers

PMID: 18302944
DOI: 10.1016/j.bbcan.2008.01.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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