Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exon structure at the human ACP1 locus supports alternative splicing model for f and s isozyme generation.

Biochemical and biophysical research communications - 15 Oct 1993

Lazaruk K D, Dissing J, Sensabaugh G F

Abstract excerpt

The human ACP1 locus encodes a genetically polymorphic cytoplasmic low-molecular-weight acid phosphatase. Each of the common alleles encodes two isoforms, f and s. Both isozymes are of equal length (157 residues) but differ in sequence over an internal 34 residue segment. Substantial portions of...

Topics

Acid Phosphatase
Alleles
Alternative Splicing
Base Sequence
Exons
Genetic Variation
Humans
Introns
Isoenzymes
Models, Genetic
Molecular Sequence Data
Sequence Homology, Nucleic Acid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 8216326
DOI: 10.1006/bbrc.1993.2269

Genes

ACP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8216326-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exon structure at the human ACP1 locus supports alternative splicing model for f and s isozyme generation.PMID 8216326Read ↗

Human red cell acid phosphatase (ACP1): the primary structure of the two pairs of isozymes encoded by the ACP1*A and ACP1*C alleles.Semantic proximity Read ↗

A TaqI site identifies the *A allele at the ACP1 locus.Semantic proximity Read ↗

Human red cell acid phosphatase (ACP1). The amino acid sequence of the two isozymes Bf and Bs encoded by the ACP1*B allele.Semantic proximity Read ↗

European ACP1*C allele has recessive deleterious effects on early life viability.Semantic proximity Read ↗

Identification of two SNPs in the 5' flanking region of the ACP1 gene and evaluation of disequilibrium among polymorphic sites.Semantic proximity Read ↗

ACP1 and human adaptability. 1. Association with common diseases: a case-control study.Semantic proximity Read ↗

A novel single-base substitution (380C>T) that activates a 5-base downstream cryptic splice-acceptor site within exon 5 in almost all transcripts in the human mitochondrial acetoacetyl-CoA thiolase gene.Semantic proximity Read ↗

Structural evidence of functional divergence in human alkaline phosphatases.Semantic proximity Read ↗

Two new frequent dimorphisms in the protein S (PROS1) gene.Semantic proximity Read ↗

Intron-exon organization of the active human protein S gene PS.alpha. and its pseudogene PS.beta.: Duplication and silencing during primate evolutionSemantic proximity Read ↗

Mutations away from splice site recognition sequences might cis-modulate alternative splicing of goat alpha s1-casein transcripts. Structural organization of the relevant gene.Semantic proximity Read ↗

Baboon lecithin cholesterol acyltransferase (LCAT): cDNA sequences of two alleles, evolution, and gene expression.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.