Article
Exon structure at the human ACP1 locus supports alternative splicing model for f and s isozyme generation.
Biochemical and biophysical research communications - 15 Oct 1993
Lazaruk K D, Dissing J, Sensabaugh G F
Abstract excerpt
The human ACP1 locus encodes a genetically polymorphic cytoplasmic low-molecular-weight acid phosphatase. Each of the common alleles encodes two isoforms, f and s. Both isozymes are of equal length (157 residues) but differ in sequence over an internal 34 residue segment. Substantial portions of the ACP1*A, *B and *C alleles common to Europeans have been sequenced. Six linearly positioned exons containing codons...
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