Article
Homonuclear (1)H-NMR assignment and structural characterization of human immunodeficiency virus type 1 Tat Mal protein.
Biopolymers - 1 Jan 2001
Grégoire C, Péloponèse J M, Esquieu D, Opi S, Campbell G, Solomiac M, Lebrun E, Lebreton J, Loret E P
Abstract excerpt
The transacting transcriptional activator (Tat) is a viral protein essential for activation of the human immunodeficiency virus (HIV) genes, and it plays an important role in HIV induced immunodeficiency. We report the NMR structural characterization of the active Tat Mal variant that belongs to a highly virulent D-subtype HIV type-1 (HIV-1) strain (Mal) found mainly in Africa. A full Tat Mal protein (87...
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